Mapping the activity of individual neurons
In a study published in the latest issue of Nature Methods, researchers from HHMI’s Janelia Farm Research Campus have produced an image showing activity of individual neurons across a larval fish brain. In the video (see below), the activity of individual neurons appear as flashes, detonating across the fish’s brain.
References: Ahrens, M. B. & Keller, P. J. (2013). Whole-brain functional imaging at cellular resolution using light-sheet microscopy. Nat. Methods, doi: 10.1038/NMETH.2434
Ahrens, M. B., et al. (2012). Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature, 485, 471-477. doi: 10.1038/nature11057 [PDF]